|Gene:||ZNF750; zinc finger protein 750|
|Summary:||This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]|
|Databases:||OMIM, VEGA, HGNC, Ensembl, GeneCard, Gene|
|Protein:||zinc finger protein 750|
|Source:||NCBIAccessed: 17 August, 2015|
What does this gene/protein do?
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Data table showing topics related to specific cancers and associated disorders. Scope includes mutations and abnormal protein expression.
|Esophageal Cancer||ZNF750 mutation in Esophageal Cancer|
Lin DC, et al (2014) reported mutation of ZNF750 as part of sequenced whole exomes (WES) study of genomic and molecular characterization of esophageal squamous cell carcinoma. 20 tumours were analysed in an initial 'discovery' cohort, and then a further 119 samples to validate. They found that ZNF750 was focally deleted in 3.4% of ESCC tumors, and ZNF750 mRNA expression was lower in esophageal tumors compared with normal tissue.
Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).
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Cite this page: Cotterill SJ. ZNF750, Cancer Genetics Web: http://www.cancer-genetics.org/ZNF750.htm Accessed:
This page in Cancer Genetics Web by Simon Cotterill is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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[Home] Page last revised: 17 August, 2015 Cancer Genetics Web, Established 1999