Down Syndrome and Cancer


Literature Analysis

Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about the topic.

  • Polymerase Chain Reaction
  • Leukaemia
  • Remission Induction
  • Base Sequence
  • Karyotyping
  • Gene Deletion
  • Myeloid Leukemia
  • Chromosome 21
  • Translocation
  • DNA Mutational Analysis
  • DNA-Binding Proteins
  • Mosaicism
  • Newborns
  • Erythroid-Specific DNA-Binding Factors
  • Infant
  • Pregnancy
  • Bone Marrow
  • Childhood Cancer
  • Chromosome Disorders
  • Mutation
  • GATA1
  • Core Binding Factor Alpha 2 Subunit
  • Acute Myeloid Leukaemia
  • Preleukemia
  • Genetic Predisposition
  • Neoplastic Cell Transformation
  • Sensitivity and Specificity
  • Leukemia, Megakaryoblastic, Acute
  • Down Syndrome
  • X-Rays
  • Alzheimer Disease
  • Aneuploidy
  • Adolescents
  • Chromosomes, Human, 21-22 and Y
  • Chromosome Aberrations
  • Risk Factors
  • Phenotype
  • FISH
  • ETS2
  • JAK2
Tag cloud generated 08 August, 2015 using data from PubMed, MeSH and CancerIndex

Mutated Genes and Abnormal Protein Expression (6)

How to use this data tableClicking on the Gene or Topic will take you to a separate more detailed page. Sort this list by clicking on a column heading e.g. 'Gene' or 'Topic'.

GATA1 Xp11.23 GF1, GF-1, NFE1, XLTT, ERYF1, NF-E1, XLANP, XLTDA, GATA-1 -GATA1 and Down Syndrome
JAK2 9p24 JTK10, THCYT3 -JAK2 mutations in Down syndrome-associated ALL
ETS2 21q22.2 ETS2IT1 -ETS2 and Down Syndrome
CRLF2 Xp22.3; Yp11.3 CRL2, TSLPR, CRLF2Y -CRLF2 and Down Syndrome
CHAT 10q11.2 CMS6, CMS1A, CMS1A2, CHOACTASE -CHAT and Down Syndrome
P2RY8 Xp22.33; Yp11.3 P2Y8 -P2RY8 and Down Syndrome

Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).

Trisomy 21 (1 links)