|Gene:||ADAM7; ADAM metallopeptidase domain 7|
|Aliases:||EAPI, GP83, GP-83, ADAM 7, ADAM-7|
|Summary:||This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]|
|Databases:||OMIM, HGNC, Ensembl, GeneCard, Gene|
|Protein:||disintegrin and metalloproteinase domain-containing protein 7|
|Source:||NCBIAccessed: 31 August, 2019|
What does this gene/protein do?
Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about the topic.
Data table showing topics related to specific cancers and associated disorders. Scope includes mutations and abnormal protein expression.
Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).
Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.
Cite this page: Cotterill SJ. ADAM7, Cancer Genetics Web: http://www.cancer-genetics.org/ADAM7.htm Accessed:
This page in Cancer Genetics Web by Simon Cotterill is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Note: content of abstracts copyright of respective publishers - seek permission where appropriate.
[Home] Page last revised: 31 August, 2019 Cancer Genetics Web, Established 1999