|Gene:||ARHGEF12; Rho guanine nucleotide exchange factor (GEF) 12|
|Summary:||Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]|
|Databases:||OMIM, VEGA, HGNC, Ensembl, GeneCard, Gene|
|Protein:||rho guanine nucleotide exchange factor 12|
|Source:||NCBIAccessed: 27 August, 2015|
What does this gene/protein do?
|Pathways:||What pathways are this gene/protein implicaed in?|